Tom Porter


Tom E Porter
Interim Associate Dean
Title
Organizational Unit
 
Interim Associate Dean
Tom E Porter
teporter@umd.edu
University of Maryland
College of Agriculture and Natural Resources
University of Maryland Extension
1202 Symons Hall
7998 Regents Drive
College Park, Maryland 20742-5551
Phone (main): 301 405-1366
Phone (alt): 410 222-3900
Fax: 301 405-2963
Associate Director
Tom E Porter
teporter@umd.edu
University of Maryland
College of Agriculture and Natural Resources
University of Maryland Extension
1202 Symons Hall
7998 Regents Drive
College Park, Maryland 20742-5551
Phone (main): 301 405-2907
Fax: 301 405-2963
Professor & Chair
Tom E Porter
teporter@umd.edu
University of Maryland
College of Agriculture and Natural Resources
Animal & Avian Sciences
1413 AnSc/AgEn Building
8127 Regents Drive
College Park, Maryland 20742-2311
Phone (main): 301 405-1366
Fax: 301 405-7980

Appointment Dr. Porter moved to the University of Maryland in 1997 as an Assistant Professor. After subsequent promotions to Associate Professor and Full Professor, he was appointed Chair of the Department of Animal and Avian Sciences in 2007. More information on the department is available at http://ansc.umd.edu/ Research Our research interests center on the neuroendocrine regulation of growth and metabolism. We have two major focuses in our research program. One major focus in our lab is the cellular differentiation of the anterior pituitary gland during embryonic development. Particular emphasis has been placed on one cell type, the somatotrophs, which secrete growth hormone. Long-range goals of this project include defining the intracellular and extracellular regulation of pituitary cell differentiation during embryonic development. A second major focus in our lab is the study of global gene expression in the neuroendocrine system. High density cDNA microarrays, containing copies of nearly all expressed genes have been developed to analyze levels of mRNA in chicken tissues. Rather than studying each gene, one at a time, this approach allows the study of all genes, simultaneously. Individual microarrays are used with RNA samples isolated from animals at different stages of development or following experimental treatments. This project is aimed at identifying those genes and gene networks involved in regulating growth and body composition in vertebrates. Teaching ANSC 644: Molecular and Cellular Endocrinology Awards and Honors

  • Dean Gordon Cairns Award for Distinguished Creative Work and Teaching in Agriculture, May 2009
  • College of Agriculture and Natural Resources Alumni Association Excellence in Instruction Award, April, 2007
  • Gamma Sigma Delta Research Award, May, 2003
  • College of Agriculture and Natural Resources Alumni Association Faculty Research Award, April, 2001
  • Research highlighted on the cover of Endocrinology, July, 2000
  • Recipient of the College of Agriculture and Natural Resources 2000 Junior Faculty Excellence Award
  • Research highlighted in an Endocrinology editorial, November, 1997
  • Poultry Science Association Research Award, 1996

Other Accomplishments

  • Author of 73 refereed scientific papers, 20 book chapters or reviews, and 122 abstracts
  • Publications cited more than 1,146 times
  • Author of 35,450 nucleotide sequence submissions to GenBank
  • Author of five cDNA microarray platform submissions to GEO (Gene Expression Omnibus)
  • Recipient of $4.7M in total funding from competitive federal grant support
  • Research mentor to 4 postdoctoral fellows, 19 graduate students, and 42 undergraduate students

Recent Publications

  • Changes in Gene Expression during Pituitary Morphogenesis and Organogenesis in the Chick Embryo. Proszkowiec-Weglarz M, Higgins SE, Porter TE. Endocrinology. 2011 Jan 14.
  • Ontogenic characterization of gene expression in the developing neuroendocrine system of the chick. Ellestad LE, Saliba J, Porter TE. Gen Comp Endocrinol. 2010 Dec 17.
  • Transcriptional profiling of hypothalamus during development of adiposity in genetically selected fat and lean chickens. Byerly MS, Simon J, Cogburn LA, Le Bihan-Duval E, Duclos MJ, Aggrey SE, Porter TE. Physiol Genomics. 2010 Jul 7;42(2):157-67.
  • Transcriptional and pathway analysis in the hypothalamus of newly hatched chicks during fasting and delayed feeding. Higgins SE, Ellestad LE, Trakooljul N, McCarthy F, Saliba J, Cogburn LA, Porter TE. BMC Genomics. 2010 Mar 9;11:162
  • Functional characterization of chicken glucocorticoid and mineralocorticoid receptors. Proszkowiec-Weglarz M, Porter TE. Am J Physiol Regul Integr Comp Physiol. 2010 May;298(5):R1257-68.
  • Byerly MS, Simon J, Lebihan-Duval E, Duclos MJ, Cogburn LA, Porter TE. Effects of BDNF, T3, and corticosterone on expression of the hypothalamic obesity gene network in vivo and in vitro. Am J Physiol Regul Integr Comp Physiol. 2009 Apr;296(4):R1180-9.
  • Heuck KA, Ellestad LE, Proudman JA, Porter TE. Somatotropin response in vitro to corticosterone and triiodothyronine during chick embryonic development: Involvement of type I and type II glucocorticoid receptors. Domest Anim Endocrinol. 2009 May;36(4):186-96.
  • Ellestad LE, Malkiewicz SA, Guthrie HD, Welch GR, Porter TE. Expression and regulation of glucocorticoid-induced leucine zipper in the developing anterior pituitary gland. J Mol Endocrinol. 2009 Feb;42(2):171-83.
  • Cogburn LA, Porter TE, Duclos MJ, Simon J, Burgess SC, Zhu JJ, Cheng HH, Dodgson JB, Burnside J. Functional genomics of the chicken--a model organism. Poult Sci. 2007 Oct;86(10):2059-94.)
  • Jenkins SA, Muchow M, Richards MP, McMurtry JP, Porter TE. Administration of adrenocorticotropic hormone during chicken embryonic development prematurely induces pituitary growth hormone cells. Endocrinology. 2007 Aug;148(8):3914-21.
  • Porter TE, Ghavam S, Muchow M, Bossis I, Ellestad L. Cloning of partial cDNAs for the chicken glucocorticoid and mineralocorticoid receptors and characterization of mRNA levels in the anterior pituitary gland during chick embryonic development. Domest Anim Endocrinol. 2007 Aug;33(2):226-39.)
  • Carre W, Wang X, Porter TE, Nys Y, Tang J, Bernberg E, Morgan R, Burnside J, Aggrey SE, Simon J, Cogburn LA. Chicken genomics resource: sequencing and annotation of 35,407 ESTs from single and multiple tissue cDNA libraries and CAP3 assembly of a chicken gene index. Physiol Genomics. 2006 May 16;25(3):514-24.
  • Ellestad LE, Carre W, Muchow M, Jenkins SA, Wang X, Cogburn LA, Porter TE. Gene expression profiling during cellular differentiation in the embryonic pituitary gland using cDNA microarrays. Physiol Genomics. 2006 May 16;25(3):414-25.
  • Porter TE, Ellestad LE, Fay A, Stewart JL, Bossis I. Identification of the chicken growth hormone-releasing hormone receptor (GHRH-R) mRNA and gene: regulation of anterior pituitary GHRH-R mRNA levels by homologous and heterologous hormones. Endocrinology. 2006 May;147(5):2535-43.
  • Porter TE, Lopez ME, Mike R, Huberty AF (2006) The increase in prolactin-secreting cells in incubating chicken hens can be mimicked by extended treatment of pituitary cells in vitro with vasoactive intestinal polypeptide (VIP). Domestic Animal Endocrinology 30 (2006) 126-134.
  • Muchow M, Bossis I, Porter TE (2005) Ontogeny of pituitary thyrotrophs and regulation by endogenous thyroid hormone feedback in the chick embryo. J Endocrinol 184:407-16
  • Porter TE (2005) Regulation of pituitary somatotroph differentiation by hormones of peripheral endocrine glands. Domestic Animal Endocrinology 29:52-62
  • Porter TE, Ellestad LE (2005) Gene expression profiling in the developing neuroendocrine system of the chick. Functional Avian Endocrinology, Dawson A, Sharp PJ (Eds.), Narosa Publishing House, New Dehli, pp. 45-56
  • Fu X, Nishimura S, Porter TE (2004) Evidence that lactotrophs do not differentiate directly from somatotrophs during chick embryonic development. J Endocrinol 183: 417-425
  • Cogburn LA, Wang X, Carre W, Rejto L, Aggrey SE, Duclos M, Simon J, Porter TE (2004) Functional genomics in chickens: Development of integrated-systems microarrays for transcriptional profiling and discovery of regulatory pathways. Comparative Functional Genomics 5: 253-261
  • Bossis I, Nishimura S, Muchow M, Porter TE (2004) Pituitary expression of type I and type II glucocorticoid receptors during chicken embryonic development and their involvement in growth hormone cell differentiation. Endocrinology 145:3523-3531.
  • Jenkins SA, Porter TE (2004) Ontogeny of the hypothalamo-pituitary-adrenocortical axis in the chicken embryo: a review. Domestic Animal Endocrinology 26:267-275.
  • Xiaoqin Fu and Tom E. Porter, Glucocorticoid Induction of Lactotrophs and Prolactin Gene Expression in Chicken Embryonic Pituitary Cells: A Delayed Response Relative to Stimulated Growth Hormone Production. Endocrinology, Mar 2004; 145: 1322 - 1330.
  • Liu L, Porter TE (2004) Endogenous thyroid hormones modulate pituitary somatotroph differentiation during chicken embryonic development. J Endocrinol 2004 180, 45-53